Discover transformative weight loss programs at Jolie Aesthetics & Wellness, featuring our once-weekly injectable treatments. Elevate your journey with other treatments in spa like MICC injections, Emsculpt sessions, and PCDC (Liquid Lipo), perfectly paired with Semaglutide and Tirzepatide for exceptional results.

Medical Weight Loss

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GLP-1

GLP-1 is a receptor agonist originally developed to support type 2 diabetes management. It works by mimicking a natural hormone (GLP-1) that helps regulate blood sugar, slows digestion, and communicates with the brain to reduce hunger and food cravings. This combination not only supports balanced blood sugar but can also make it easier to manage weight.
Unlike older appetite suppressants, GLP-1 medications act on a different pathway and have shown impressive results for both metabolic health and weight management.
- Mimic the natural GLP-1 hormone to regulate blood sugar
- Slow down digestion, helping you feel fuller for longer
- Reduce appetite and curb food cravings
- Support balanced metabolism and healthier eating habits
- Promote sustainable, clinically proven weight management
GLP-1 is administered via a once-weekly subcutaneous (just under the skin) injection. Your provider will start at a low dose and adjust gradually—no more frequently than every 4 weeks—to minimize side effects and help your body adapt.
Common injection sites include:
- Abdomen
- Thigh
- Upper arm
Your provider will guide you on technique, site rotation, and storage.
- Semaglutide is not a stimulant or quick-fix diet drug—it works best when combined with lifestyle changes.
- You’ll need regular check-ins with your provider for dose adjustments and progress monitoring.
- Common side effects may include nausea, constipation, or fatigue, especially when increasing your dose.
- Not recommended during pregnancy or for individuals with a personal or family history of medullary thyroid carcinoma.
We’ll review your health history thoroughly to ensure Semaglutide is the right fit for your weight loss journey.

GLP-1/GIP

Tirzepatide (brand name: Zepbound) is a once-weekly injection used to support weight loss in adults with obesity or overweight individuals who may also have conditions like type 2 diabetes, high blood pressure, sleep apnea, high cholesterol, or cardiovascular disease.
It belongs to a unique class of medications that activate both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors—offering dual-action metabolic support. By enhancing insulin release and suppressing glucagon (a hormone that raises blood sugar), it improves blood sugar control and reduces hunger signals.
Tirzepatide helps regulate blood sugar while supporting weight loss through multiple mechanisms:
- Appetite Suppression: Mimics hormones that help control hunger and increase satiety
- Slows Gastric Emptying: Keeps you feeling full longer, reducing calorie intake
- Fat-Burning Support: Helps keep blood sugar low, allowing the body to more efficiently burn stored fat
- Insulin Optimization: Enhances your body’s natural ability to release insulin when needed
This makes Tirzepatide a comprehensive metabolic therapy—not just a weight loss injection.
Tirzepatide is injected once weekly under the skin (subcutaneously). Your provider will start at a low dose and gradually increase it—no more often than every 4 weeks—to minimize side effects and support your body’s adjustment.
Injection sites include:
- Abdomen
- Thigh
- Upper arm
It’s recommended to rotate injection sites weekly for best results and comfort.
- Effective Weight Reduction: Shown to produce significant weight loss in clinical trials
- Appetite Control: Helps reduce cravings and supports mindful eating
- Improved Body Composition: May reduce fat mass while preserving lean muscle
- Cardiometabolic Health: Improves blood pressure, cholesterol, and blood sugar markers
- Sustainable & Convenient: Once-weekly dosing helps with long-term adherence
Tirzepatide supports more than just weight loss—it’s a strategic approach to improving metabolic health and long-term wellness.
- Must be paired with healthy lifestyle changes for optimal results
- Not recommended during pregnancy or for those with a history of medullary thyroid carcinoma
- Side effects may include nausea, constipation, fatigue, or digestive changes
- Regular follow-up is important to monitor dosing and progress
Your provider will ensure that Tirzepatide is safe and appropriate based on your health history and goals.